The contest marks the 14th all-time meeting between Tulane and Houston, with the Cougars leading the series, 10-4.
Tulane LB Evan Lee started his 24th consecutive game, the longest active streak for the Green Wave. C Michael Parenton started his 23rd consecutive game, while Andrew Nierman made his 21th consecutive start; senior DE Reggie Scott's streak of consecutive starts ended at 20, due to injury.
Tulane has not been shutout in a game in the last 74 games, a streak dating back to Sept. 28, 2002 at No. 3 Texas (49-0).
Senior Michael Batiste has caught at least one pass in nine straight games this season, the only wide receiver to do so.
Logan Kelley recorded his sixth sack of the season, a team-high for the Green Wave.
David Skehan picked up his fifth career fumble, knocked loose by Corey Sonnier, who tallied his second career forced fumble (his first came at Alabama in the season opener).
Nathan Austin recorded his his first career touchdown (11 yards) to put Tulane on the board with 10:03 in the second quarter.
Travis Burks intercepted a pass for the second consecutive game with 31 seconds to go in the first half, to give Tulane the ball on the Houston 34-yard line.
Redshirt freshman Joe Kemp suffered a broken left collarbone in the second quarter of play.
Redshirt freshmen Taylor Echols returned his first collegiate kickoff in the third quarter for 48 yards.
Alan Mitchell recorded a career-long 28 yard rush in the third quarter to take Tulane to the Houston 5-yard line. The carry marked his second consecutive game with a rush after carrying the ball twice for 13 yards against LSU last week.
Case Keenum became the first quarterback to throw for over 300 yards against Tulane this season; Trevor Vittatoe of UTEP previously held the record for most yards in the air against Tulane this season with 296.
The loss in Houston marks the third straight loss in the Cougar's home stadium for Tulane.